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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1G2
All Species:
40.61
Human Site:
Y574
Identified Species:
74.44
UniProt:
O75843
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75843
NP_003908.1
785
87117
Y574
Y
D
T
L
F
R
K
Y
D
H
M
R
A
A
I
Chimpanzee
Pan troglodytes
XP_001163717
785
87058
Y574
Y
D
T
L
F
R
K
Y
D
H
M
R
A
A
I
Rhesus Macaque
Macaca mulatta
XP_001109007
785
86931
Y574
Y
D
T
L
F
R
K
Y
D
H
M
R
A
A
I
Dog
Lupus familis
XP_537377
787
87286
Y574
Y
N
T
L
F
R
K
Y
D
H
M
R
A
A
I
Cat
Felis silvestris
Mouse
Mus musculus
O88512
791
87846
Y574
Y
N
T
L
F
Q
K
Y
D
H
M
R
A
A
I
Rat
Rattus norvegicus
P18484
938
104026
V580
V
E
L
Q
Q
R
A
V
E
Y
L
R
L
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509435
822
91369
Y573
Y
N
A
L
F
K
K
Y
D
H
M
R
S
A
L
Chicken
Gallus gallus
NP_001006132
821
91444
Y576
Y
N
A
L
F
K
K
Y
D
H
M
R
P
A
L
Frog
Xenopus laevis
NP_001083997
812
90423
Y573
Y
N
A
L
F
K
K
Y
D
H
M
R
S
A
L
Zebra Danio
Brachydanio rerio
NP_955976
819
90933
Y572
Y
N
A
L
F
K
K
Y
D
H
M
R
P
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
T592
Q
L
S
I
V
A
S
T
D
V
L
A
T
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792773
959
106235
Y684
F
M
S
L
T
K
S
Y
K
H
I
A
G
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12028
832
93606
S617
Y
E
I
F
F
N
Q
S
I
S
V
K
K
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97
90.3
N.A.
86.4
24
N.A.
60.4
59.9
59.3
60.3
N.A.
24
N.A.
N.A.
42
Protein Similarity:
100
99.8
97.8
94.2
N.A.
91.7
44.5
N.A.
75.5
75.4
76.4
75.5
N.A.
44.2
N.A.
N.A.
58.8
P-Site Identity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
66.6
66.6
66.6
66.6
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
93.3
86.6
93.3
86.6
N.A.
33.3
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
0
0
8
8
0
0
0
0
16
39
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
24
0
0
0
0
0
0
77
0
0
0
0
0
0
% D
% Glu:
0
16
0
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
8
0
0
8
77
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
8
0
8
0
0
8
47
% I
% Lys:
0
0
0
0
0
39
70
0
8
0
0
8
8
0
0
% K
% Leu:
0
8
8
77
0
0
0
0
0
0
16
0
8
0
47
% L
% Met:
0
8
0
0
0
0
0
0
0
0
70
0
0
0
0
% M
% Asn:
0
47
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
16
8
0
% P
% Gln:
8
0
0
8
8
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
39
0
0
0
0
0
77
0
0
0
% R
% Ser:
0
0
16
0
0
0
16
8
0
8
0
0
16
8
0
% S
% Thr:
0
0
39
0
8
0
0
8
0
0
0
0
8
0
8
% T
% Val:
8
0
0
0
8
0
0
8
0
8
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
77
0
0
0
0
0
0
77
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _